Cagrilintide: What It Is and How It's Being Studied for Weight Loss New Weight Loss Drug CagriSema Shows Impressive Results in Clinical Trials Cagrilintide Combined with Semaglutide: A New Approach for Treatment of Obesity and Type 2 Diabetes ClinicSearch Cagrilintide is an amylin analogue that helps regulate appetite. In a randomized trial of over 3400 patients who were overweight or obese and had 1 weight related complication, individuals assigned to a combination Combined GLP 1 amylin analog bests monotherapy for HbA1c drop, weight loss in diabetes CagrilintideSemaglutide in Adults with Overweight or Obesity and Type 2 Diabetes New England Journal of Medicine