Differential Diagnosis of Pigmented Lesions in the Oral Mucosa: A Clinical Based Overview and Narrative Review Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Mystery behind labial and oral melanotic macules: Clinical, dermoscopic and pathological aspects of Laugier Hunziker syndrome Removal of a melanotic macule on the lip with Q switched laser before and after photos taken 3 months apart, after a single treatment #dermatologist #dermatology #laser #laserderm #ottawaskincare #toc #ottawalaserclinic #cosmetics # Melanocytic nevi and malignant melanoma Medizinonline Pigmented Lesion on the Hard Palate AFP