The Multiple Roles of Glucose 6 Phosphate Dehydrogenase in Tumorigenesis and Cancer Chemoresistance The potential link between inherited G6PD deficiency, oxidative stress, and vitamin D deficiency and the racial inequities in mortality associated with COVID 19 ScienceDirect The Controversial Role of Glucose6Phosphate Dehydrogenase Deficiency on Cardiovascular Disease: A Narrative Review Dore 2021 Oxidative Medicine and Cellular Longevity Wiley Online Library The Pentose Phosphate Pathway & G6PD Deficiency , Blog: https: bit.ly pentosephosphatepathway; https: bit.ly g6pddeficiency, YouTube: https: youtu.be ITy2gkUD7eM , Key points about the Pentose Hepatic Glucose 6 Phosphate Dehydrogenase (G6PD) plays a pivotal role in the Pentose Phosphate Pathway, generating NADPH for antioxidant defense and supporting nucleotide & amino acid biosynthesis. Diabetes causes inhibition of glucose 6 phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex American Journal of Physiology Renal Physiology American Physiological Society