Since Tylenol is such a hot topic right now, did you know it depletes glutathione levels? When your body processes Tylenol in the liver, one of the pathways creates a toxic byproduct. To neutralize Acetaminophen at low doses depletes airway glutathione and alters respiratory reflex responses Smith 2013 The FASEB Journal Wiley Online Library Acetaminophen MSK Medbullets Step 1 Reducing the effects of drug toxicity on glutathione metabolism ScienceDirect Is Tylenol Safe During Pregnancy? Risk Factors, Not Causation USMLE Step 2 CK Question of the Day: Altered Mental State After Over the counter pain reliever and Prescription Hydrocodone acetaminophen Osmosis Blog